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Cell Autonomous and Non-autonomous Effects of Senescent Cells in the Skin

Human and mouse skin accumulate senescent cells in both the epidermis and dermis during aging. When chronically present, senescent cells are thought to enhance the age-dependent deterioration of the skin during extrinsic and intrinsic aging. However, when transiently present, senescent cells promote...

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Detalles Bibliográficos
Autores principales: Demaria, Marco, Desprez, Pierre Yves, Campisi, Judith, Velarde, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466004/
https://www.ncbi.nlm.nih.gov/pubmed/25855157
http://dx.doi.org/10.1038/jid.2015.108