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Crystal structure of human profilaggrin S100 domain and identification of target proteins annexin II, stratifin and hsp27
The fused-type S100 protein profilaggrin and its proteolytic products including filaggrin are important in the formation of a normal epidermal barrier; however, the specific function of the S100 calcium-binding domain in profilaggrin biology is poorly understood. To explore its molecular function, w...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466033/ https://www.ncbi.nlm.nih.gov/pubmed/25760235 http://dx.doi.org/10.1038/jid.2015.102 |