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Crystal structure of human profilaggrin S100 domain and identification of target proteins annexin II, stratifin and hsp27

The fused-type S100 protein profilaggrin and its proteolytic products including filaggrin are important in the formation of a normal epidermal barrier; however, the specific function of the S100 calcium-binding domain in profilaggrin biology is poorly understood. To explore its molecular function, w...

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Detalles Bibliográficos
Autores principales: Bunick, Christopher G, Presland, Richard B, Lawrence, Owen T, Pearton, David J, Milstone, Leonard M, Steitz, Thomas A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466033/
https://www.ncbi.nlm.nih.gov/pubmed/25760235
http://dx.doi.org/10.1038/jid.2015.102