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NFκB-regulation of c-FLIP promotes TNFα-mediated RAF inhibitor resistance in melanoma
Targeted inhibitors elicit heterogeneous clinical responses in genetically stratified groups of patients. While most studies focus on tumor intrinsic properties, factors in the tumor microenvironment were recently found to modulate the response to inhibitors. Here, we show that in cutaneous BRAF V60...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466037/ https://www.ncbi.nlm.nih.gov/pubmed/25751672 http://dx.doi.org/10.1038/jid.2015.91 |