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The Cdc42 Effector Kinase PAK4 Localizes to Cell-Cell Junctions and Contributes to Establishing Cell Polarity

The serine/threonine kinase PAK4 is a Cdc42 effector whose role is not well understood; overexpression of PAK4 has been associated with some cancers, and there are reports that correlate kinase level with increased cell migration in vitro. Here we report that PAK4 is primarily associated with cell-c...

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Detalles Bibliográficos
Autores principales: Selamat, Widyawilis, Tay, Pei-Ling Felicia, Baskaran, Yohendran, Manser, Ed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466050/
https://www.ncbi.nlm.nih.gov/pubmed/26068882
http://dx.doi.org/10.1371/journal.pone.0129634