Real-time tRNA transit on single translating ribosomes at codon resolution

Translation by the ribosome occurs by a complex mechanism involving the coordinated interaction of multiple nucleic acid and protein ligands. Here we have used zero-mode waveguides (ZMWs) and sophisticated detection instrumentation to allow real-time observation of translation at physiologically-rel...

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Detalles Bibliográficos
Autores principales: Uemura, Sotaro, Aitken, Colin Echeverría, Korlach, Jonas, Flusberg, Benjamin A., Turner, Stephen W., Puglisi, Joseph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466108/
https://www.ncbi.nlm.nih.gov/pubmed/20393556
http://dx.doi.org/10.1038/nature08925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466108/
https://www.ncbi.nlm.nih.gov/pubmed/20393556
http://dx.doi.org/10.1038/nature08925

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