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New strategies for targeting matrix metalloproteinases
The development of matrix metalloproteinase (MMP) inhibitors has often been frustrated by a lack of specificity and subsequent off-target effects. More recently, inhibitor design has considered secondary binding sites (exosites) to improve specificity. Small molecules and peptides have been develope...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466128/ https://www.ncbi.nlm.nih.gov/pubmed/25595836 http://dx.doi.org/10.1016/j.matbio.2015.01.002 |