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Proteomic Identification of DNA-PK Involvement within the RET Signaling Pathway

Constitutive activation of the Rearranged during Transfection (RET) proto-oncogene leads to the development of MEN2A medullary thyroid cancer (MTC). The relatively clear genotype/phenotype relationship seen with RET mutations and the development of MEN2A is unusual in the fact that a single gene act...

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Detalles Bibliográficos
Autores principales: Burdine, Lyle J., Burdine, Marie Schluterman, Moreland, Linley, Fogel, Brad, Orr, Lisa M., James, Jennifer, Turnage, Richard H., Tackett, Alan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466258/
https://www.ncbi.nlm.nih.gov/pubmed/26065416
http://dx.doi.org/10.1371/journal.pone.0127943