HIV-1 Coreceptor Usage Assessment by Ultra-Deep Pyrosequencing and Response to Maraviroc

BACKGROUND: Maraviroc is an HIV entry inhibitor that alters the conformation of CCR5 and is poorly efficient in patients infected by viruses that use CXCR4 as an entry coreceptor. The goal of this study was to assess the capacity of ultra-deep pyrosequencing (UDPS) and different data analysis approa...

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Detalles Bibliográficos
Autores principales: Rodriguez, Christophe, Soulié, Cathia, Marcelin, Anne-Geneviève, Calvez, Vincent, Descamps, Diane, Charpentier, Charlotte, Flandre, Philippe, Recordon-Pinson, Patricia, Bellecave, Pantxika, Pawlotsky, Jean-Michel, Masquelier, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466260/
https://www.ncbi.nlm.nih.gov/pubmed/26068869
http://dx.doi.org/10.1371/journal.pone.0127816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466260/
https://www.ncbi.nlm.nih.gov/pubmed/26068869
http://dx.doi.org/10.1371/journal.pone.0127816

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