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Effects of Nandrolone in the Counteraction of Skeletal Muscle Atrophy in a Mouse Model of Muscle Disuse: Molecular Biology and Functional Evaluation

Muscle disuse produces severe atrophy and a slow-to-fast phenotype transition in the postural Soleus (Sol) muscle of rodents. Antioxidants, amino-acids and growth factors were ineffective to ameliorate muscle atrophy. Here we evaluate the effects of nandrolone (ND), an anabolic steroid, on mouse ske...

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Detalles Bibliográficos
Autores principales: Camerino, Giulia Maria, Desaphy, Jean-François, De Bellis, Michela, Capogrosso, Roberta Francesca, Cozzoli, Anna, Dinardo, Maria Maddalena, Caloiero, Roberta, Musaraj, Kejla, Fonzino, Adriano, Conte, Elena, Jagerschmidt, Catherine, Namour, Florence, Liantonio, Antonella, De Luca, Annamaria, Conte Camerino, Diana, Pierno, Sabata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466268/
https://www.ncbi.nlm.nih.gov/pubmed/26066046
http://dx.doi.org/10.1371/journal.pone.0129686