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Hey bHLH Proteins Interact with a FBXO45 Containing SCF Ubiquitin Ligase Complex and Induce Its Translocation into the Nucleus

The Hey protein family, comprising Hey1, Hey2 and HeyL in mammals, conveys Notch signals in many cell types. The helix-loop-helix (HLH) domain as well as the Orange domain, mediate homo- and heterodimerization of these transcription factors. Although distinct interaction partners have been identifie...

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Detalles Bibliográficos
Autores principales: Salat, Daniela, Winkler, Anja, Urlaub, Henning, Gessler, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466309/
https://www.ncbi.nlm.nih.gov/pubmed/26068074
http://dx.doi.org/10.1371/journal.pone.0130288