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Improving Detection of Arrhythmia Drug-Drug Interactions in Pharmacovigilance Data through the Implementation of Similarity-Based Modeling

Identification of Drug-Drug Interactions (DDIs) is a significant challenge during drug development and clinical practice. DDIs are responsible for many adverse drug effects (ADEs), decreasing patient quality of life and causing higher care expenses. DDIs are not systematically evaluated in pre-clini...

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Detalles Bibliográficos
Autores principales: Vilar, Santiago, Lorberbaum, Tal, Hripcsak, George, Tatonetti, Nicholas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466327/
https://www.ncbi.nlm.nih.gov/pubmed/26068584
http://dx.doi.org/10.1371/journal.pone.0129974