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Disruption of bbe02 by Insertion of a Luciferase Gene Increases Transformation Efficiency of Borrelia burgdorferi and Allows Live Imaging in Lyme Disease Susceptible C3H Mice

Lyme disease is the most prevalent tick-borne disease in North America and Europe. The causative agent, Borrelia burgdorferi persists in the white-footed mouse. Infection with B. burgdorferi can cause acute to persistent multisystemic Lyme disease in humans. Some disease manifestations are also exhi...

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Detalles Bibliográficos
Autores principales: Chan, Kamfai, Alter, Laura, Barthold, Stephen W., Parveen, Nikhat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466376/
https://www.ncbi.nlm.nih.gov/pubmed/26069970
http://dx.doi.org/10.1371/journal.pone.0129532