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Canonical and Noncanonical Sites Determine NPT2A Binding Selectivity to NHERF1 PDZ1

Na(+)/H(+) Exchanger Regulatory Factor-1 (NHERF1) is a scaffolding protein containing 2 PDZ domains that coordinates the assembly and trafficking of transmembrane receptors and ion channels. Most target proteins harboring a C-terminus recognition motif bind more-or-less equivalently to the either PD...

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Detalles Bibliográficos
Autores principales: Mamonova, Tatyana, Zhang, Qiangmin, Khajeh, Jahan Ali, Bu, Zimei, Bisello, Alessandro, Friedman, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466390/
https://www.ncbi.nlm.nih.gov/pubmed/26070212
http://dx.doi.org/10.1371/journal.pone.0129554