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NK-, NKT- and CD8-Derived IFNγ Drives Myeloid Cell Activation and Erythrophagocytosis, Resulting in Trypanosomosis-Associated Acute Anemia

African trypanosomes are the causative agents of Human African Trypanosomosis (HAT/Sleeping Sickness) and Animal African Trypanosomosis (AAT/Nagana). A common hallmark of African trypanosome infections is inflammation. In murine trypanosomosis, the onset of inflammation occurs rapidly after infectio...

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Detalles Bibliográficos
Autores principales: Cnops, Jennifer, De Trez, Carl, Stijlemans, Benoit, Keirsse, Jiri, Kauffmann, Florence, Barkhuizen, Mark, Keeton, Roanne, Boon, Louis, Brombacher, Frank, Magez, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466398/
https://www.ncbi.nlm.nih.gov/pubmed/26070118
http://dx.doi.org/10.1371/journal.ppat.1004964