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A Novel Osteogenic Activity of Suberoylanilide Hydroxamic Acid is Synergized by BMP-2

BACKGROUND: Many histone deacetylase (HDAC) inhibitors are well recognized as potential anti-cancer drugs. Inhibition of HDACs induces temporal transcription or epigenetic control, thus regulating many different biological responses. Here, we investigated the osteogenic effect of the HDAC inhibitor...

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Detalles Bibliográficos
Autores principales: Lee, Zang Hee, Kim, Hyun-Jung, Ryoo, Hyun Mo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Bone and Mineral Research 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466445/
https://www.ncbi.nlm.nih.gov/pubmed/26082914
http://dx.doi.org/10.11005/jbm.2015.22.2.51