PERK-mediated Autophagy in Osteosarcoma Cells Resists ER Stress-induced Cell Apoptosis

Osteosarcoma is a bone cancer that develops commonly in children and adolescents. However, osteosarcoma treatments often fail by the development of chemoresistance to apoptosis, and the molecular mechanisms remain unclear. In this study, we propose that autophagy is responsible for osteosarcomatous...

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Detalles Bibliográficos
Autores principales: Ji, Guang-rong, Yu, Nai-chun, Xue, Xiang, Li, Zong-guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466461/
https://www.ncbi.nlm.nih.gov/pubmed/26078722
http://dx.doi.org/10.7150/ijbs.11100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466461/
https://www.ncbi.nlm.nih.gov/pubmed/26078722
http://dx.doi.org/10.7150/ijbs.11100

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