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PERK-mediated Autophagy in Osteosarcoma Cells Resists ER Stress-induced Cell Apoptosis
Osteosarcoma is a bone cancer that develops commonly in children and adolescents. However, osteosarcoma treatments often fail by the development of chemoresistance to apoptosis, and the molecular mechanisms remain unclear. In this study, we propose that autophagy is responsible for osteosarcomatous...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Ivyspring International Publisher
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466461/ https://www.ncbi.nlm.nih.gov/pubmed/26078722 http://dx.doi.org/10.7150/ijbs.11100 |