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Novel EPHB4 Receptor Tyrosine Kinase Mutations and Kinomic Pathway Analysis in Lung Cancer

Lung cancer outcomes remain poor despite the identification of several potential therapeutic targets. The EPHB4 receptor tyrosine kinase (RTK) has recently emerged as an oncogenic factor in many cancers, including lung cancer. Mutations of EPHB4 in lung cancers have previously been identified, thoug...

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Detalles Bibliográficos
Autores principales: Ferguson, Benjamin D., Carol Tan, Yi-Hung, Kanteti, Rajani S., Liu, Ren, Gayed, Matthew J., Vokes, Everett E., Ferguson, Mark K., John Iafrate, A., Gill, Parkash S., Salgia, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466581/
https://www.ncbi.nlm.nih.gov/pubmed/26073592
http://dx.doi.org/10.1038/srep10641