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Novel EPHB4 Receptor Tyrosine Kinase Mutations and Kinomic Pathway Analysis in Lung Cancer
Lung cancer outcomes remain poor despite the identification of several potential therapeutic targets. The EPHB4 receptor tyrosine kinase (RTK) has recently emerged as an oncogenic factor in many cancers, including lung cancer. Mutations of EPHB4 in lung cancers have previously been identified, thoug...
Autores principales: | Ferguson, Benjamin D., Carol Tan, Yi-Hung, Kanteti, Rajani S., Liu, Ren, Gayed, Matthew J., Vokes, Everett E., Ferguson, Mark K., John Iafrate, A., Gill, Parkash S., Salgia, Ravi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466581/ https://www.ncbi.nlm.nih.gov/pubmed/26073592 http://dx.doi.org/10.1038/srep10641 |
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