Pyruvate kinase M2 prevents apoptosis via modulating Bim stability and associates with poor outcome in hepatocellular carcinoma

Pyruvate kinase M2 (PKM2) contributes to the Warburg effect, a hallmark of cancer. We showed that PKM2 levels were correlated with overall survival (hazard ration = 1.675, 95% confidence interval: 1.389–2.019, P < 0.001) and disease-free survival (hazard ration = 1.573, 95% confidence interval: 1...

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Detalles Bibliográficos
Autores principales: Hu, Wen, Lu, Shi-Xun, Li, Min, Zhang, Chao, Liu, Li-Li, Fu, Jia, Jin, Jie-Tian, Luo, Rong-Zhen, Zhang, Chris Zhiyi, Yun, Jing-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466635/
https://www.ncbi.nlm.nih.gov/pubmed/25788265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466635/
https://www.ncbi.nlm.nih.gov/pubmed/25788265

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