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Distinct anti-oncogenic effect of various microRNAs in different mouse models of liver cancer

Deregulation of microRNAs (miRNAs) is a typical feature of human hepatocellular carcinoma (HCC). However, the in vivo relevance of miRNAs along hepatocarcinogenesis remains largely unknown. Here, we show that liver tumors induced in mice by c-Myc overexpression or AKT/Ras co-expression exhibit disti...

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Detalles Bibliográficos
Autores principales: Tao, Junyan, Ji, Junfang, Li, Xiaolei, Ding, Ning, Wu, Heng, Liu, Yan, Wang, XinWei, Calvisi, Diego F., Song, Guisheng, Chen, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466663/
https://www.ncbi.nlm.nih.gov/pubmed/25762642