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TNKS1BP1 functions in DNA double-strand break repair though facilitating DNA-PKcs autophosphorylation dependent on PARP-1

TNKS1BP1 was originally identified as an interaction protein of tankyrase 1, which belongs to the poly(ADP-ribose) polymerase (PARP) superfamily. PARP members play important roles for example in DNA repair, telomere stability and mitosis regulation. Although the TNKS1BP1 protein was considered to be...

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Detalles Bibliográficos
Autores principales: Zou, Lian-Hong, Shang, Zeng-Fu, Tan, Wei, Liu, Xiao-Dan, Xu, Qin-Zhi, Song, Man, Wang, Yu, Guan, Hua, Zhang, Shi-Meng, Yu, Lan, Zhong, Cai-Gao, Zhou, Ping-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466666/
https://www.ncbi.nlm.nih.gov/pubmed/25749521