Cargando…

TNKS1BP1 functions in DNA double-strand break repair though facilitating DNA-PKcs autophosphorylation dependent on PARP-1

TNKS1BP1 was originally identified as an interaction protein of tankyrase 1, which belongs to the poly(ADP-ribose) polymerase (PARP) superfamily. PARP members play important roles for example in DNA repair, telomere stability and mitosis regulation. Although the TNKS1BP1 protein was considered to be...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zou, Lian-Hong, Shang, Zeng-Fu, Tan, Wei, Liu, Xiao-Dan, Xu, Qin-Zhi, Song, Man, Wang, Yu, Guan, Hua, Zhang, Shi-Meng, Yu, Lan, Zhong, Cai-Gao, Zhou, Ping-Kun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466666/ https://www.ncbi.nlm.nih.gov/pubmed/25749521

Ejemplares similares

Overexpression of TNKS1BP1 in lung cancers and its involvement in homologous recombination pathway of DNA double‐strand breaks
por: Tan, Wei, et al.
Publicado: (2017)

BRCA1 modulates the autophosphorylation status of DNA-PKcs in S phase of the cell cycle
por: Davis, Anthony J., et al.
Publicado: (2014)

HUWE1-dependent DNA-PKcs neddylation modulates its autophosphorylation in DNA damage response
por: Guo, Zongpei, et al.
Publicado: (2020)

Autophosphorylation of DNA-PK(CS) regulates its dynamics at DNA double-strand breaks
por: Uematsu, Naoya, et al.
Publicado: (2007)

Non-redundant Functions of ATM and DNA-PKcs in Response to DNA Double-Strand Breaks
por: Caron, Pierre, et al.
Publicado: (2015)

Pre‐rRNA Facilitates TopBP1‐Mediated DNA Double‐Strand Break Response
por: Xin, Di, et al.
Publicado: (2023)

ARF induction in response to DNA strand breaks is regulated by PARP1
por: Orlando, Giulia, et al.
Publicado: (2014)

Fatty acid oxidation facilitates DNA double-strand break repair by promoting PARP1 acetylation
por: Yang, Seungyeon, et al.
Publicado: (2023)

DNA-Dependent Protein Kinase Catalytic Subunit (DNA-PKcs): Beyond the DNA Double-Strand Break Repair
por: Lee, Ye-Rim, et al.
Publicado: (2023)

The fructose-bisphosphate, Aldolase A (ALDOA), facilitates DNA-PKcs and ATM kinase activity to regulate DNA double-strand break repair
por: Sobanski, Thais, et al.
Publicado: (2023)

A Mathematical Model for the Detection Mechanism of DNA Double-Strand Breaks Depending on Autophosphorylation of ATM
por: Mouri, Kazunari, et al.
Publicado: (2009)

Targeting DNA double strand break repair with hyperthermia and DNA-PKcs inhibition to enhance the effect of radiation treatment
por: van Oorschot, Bregje, et al.
Publicado: (2016)

Inhibiting DNA-PKcs in a non-homologous end-joining pathway in response to DNA double-strand breaks
por: Dong, Jun, et al.
Publicado: (2017)

Structural Basis of Detection and Signaling of DNA Single-Strand Breaks by Human PARP-1
por: Eustermann, Sebastian, et al.
Publicado: (2015)

The PARP3- and ATM-dependent phosphorylation of APLF facilitates DNA double-strand break repair
por: Fenton, Amanda L., et al.
Publicado: (2013)

Acetylation of 53BP1 dictates the DNA double strand break repair pathway
por: Guo, Xiang, et al.
Publicado: (2018)

Preventing Damage Limitation: Targeting DNA-PKcs and DNA Double-Strand Break Repair Pathways for Ovarian Cancer Therapy
por: Dungl, Daniela A., et al.
Publicado: (2015)

PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways
por: Wang, Minli, et al.
Publicado: (2006)

Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaks
por: Cheng, Qiao, et al.
Publicado: (2011)

Poly(ADP-ribose) polymerase (PARP-1) is not involved in DNA double-strand break recovery
por: Noël, Georges, et al.
Publicado: (2003)

Structural dynamics of DNA strand break sensing by PARP-1 at a single-molecule level
por: Sefer, Anna, et al.
Publicado: (2022)

Haploinsufficiency of ZNF251 causes DNA-PKcs-dependent resistance to PARP inhibitors in BRCA1-mutated cancer cells
por: Li, Huan, et al.
Publicado: (2023)

Tying the loose ends together in DNA double strand break repair with 53BP1
por: Adams, Melissa M, et al.
Publicado: (2006)

Spatiotemporal dynamics of 53BP1 dimer recruitment to a DNA double strand break
por: Lou, Jieqiong, et al.
Publicado: (2020)

HDGFRP3 interaction with 53BP1 promotes DNA double-strand break repair
por: Zhang, Zhen, et al.
Publicado: (2023)

Single-molecule force spectroscopy reveals binding and bridging dynamics of PARP1 and PARP2 at DNA double-strand breaks
por: Bell, Nicholas A. W., et al.
Publicado: (2023)

Super-resolution imaging identifies PARP1 and the Ku complex acting as DNA double-strand break sensors
por: Yang, Guang, et al.
Publicado: (2018)

JNK Phosphorylates SIRT6 to Stimulate DNA Double-Strand Break Repair in Response to Oxidative Stress by Recruiting PARP1 to DNA Breaks
por: Van Meter, Michael, et al.
Publicado: (2016)

PARP2 controls double-strand break repair pathway choice by limiting 53BP1 accumulation at DNA damage sites and promoting end-resection
por: Fouquin, Alexis, et al.
Publicado: (2017)

Novel PNKP mutations causing defective DNA strand break repair and PARP1 hyperactivity in MCSZ
por: Kalasova, Ilona, et al.
Publicado: (2019)

53BP1 Mediates the Fusion of Mammalian Telomeres Rendered Dysfunctional by DNA-PKcs Loss or Inhibition
por: Rybanska-Spaeder, Ivana, et al.
Publicado: (2014)

SMCHD1 accumulates at DNA damage sites and facilitates the repair of DNA double-strand breaks
por: Coker, Heather, et al.
Publicado: (2014)

TRABID overexpression enables synthetic lethality to PARP inhibitor via prolonging 53BP1 retention at double-strand breaks
por: Ma, Jian, et al.
Publicado: (2023)

The CSB chromatin remodeler regulates PARP1- and PARP2-mediated single-strand break repair at actively transcribed DNA regions
por: Bilkis, Rabeya, et al.
Publicado: (2023)

SAMHD1 deacetylation by SIRT1 promotes DNA end resection by facilitating DNA binding at double-strand breaks
por: Kapoor-Vazirani, Priya, et al.
Publicado: (2022)

DNA double-strand break-derived RNA drives TIRR/53BP1 complex dissociation
por: Ketley, Ruth F., et al.
Publicado: (2022)

Regulation of pairing between broken DNA-containing chromatin regions by Ku80, DNA-PKcs, ATM, and 53BP1
por: Yamauchi, Motohiro, et al.
Publicado: (2017)

Bridging of nucleosome-proximal DNA double-strand breaks by PARP2 enhances its interaction with HPF1
por: Gaullier, Guillaume, et al.
Publicado: (2020)

CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks
por: Rother, Magdalena B., et al.
Publicado: (2020)

Deciphering the functional mechanism of zinc ions of PARP1 binding with single strand breaks and double strand breaks
por: Sun, Shuya, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_3i8cr45vddkuaplr2p92rep3nc