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High neuropeptide Y release associates with Ewing sarcoma bone dissemination - in vivo model of site-specific metastases

Ewing sarcoma (ES) develops in bones or soft tissues of children and adolescents. The presence of bone metastases is one of the most adverse prognostic factors, yet the mechanisms governing their formation remain unclear. As a transcriptional target of EWS-FLI1, the fusion protein driving ES transfo...

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Detalles Bibliográficos
Autores principales: Hong, Sung-Hyeok, Tilan, Jason U., Galli, Susana, Izycka-Swieszewska, Ewa, Polk, Taylor, Horton, Meredith, Mahajan, Akanksha, Christian, David, Jenkins, Shari, Acree, Rachel, Connors, Katherine, Ledo, Phuong, Lu, Congyi, Lee, Yi-Chien, Rodriguez, Olga, Toretsky, Jeffrey A., Albanese, Chris, Kitlinska, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466675/
https://www.ncbi.nlm.nih.gov/pubmed/25714031