Inhibition of PI3K/AKT/mTOR axis disrupts oxidative stress-mediated survival of melanoma cells

Elevated oxidative stress in cancer cells contributes to hyperactive proliferation and enhanced survival, which can be exploited using agents that increase reactive oxygen species (ROS) beyond a threshold level. Here we show that melanoma cells exhibit an oxidative stress phenotype compared with nor...

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Detalles Bibliográficos
Autores principales: Hambright, Heather G., Meng, Peng, Kumar, Addanki P., Ghosh, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466678/
https://www.ncbi.nlm.nih.gov/pubmed/25749517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466678/
https://www.ncbi.nlm.nih.gov/pubmed/25749517

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