EGF-reduced Wnt5a transcription induces epithelial-mesenchymal transition via Arf6-ERK signaling in gastric cancer cells

Wnt5a, a ligand for activating the non-canonical Wnt signaling pathway, is commonly associated with Epithelial-to-mesenchymal transition (EMT) in cancer cell metastasis. Here, we show that downregulation of Wnt5a mRNA and protein by EGF is necessary for EGF-induced EMT in gastric cancer SGC-7901 cel...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yujie, Du, Jun, Zheng, Jianchao, Liu, Jiaojing, Xu, Rui, Shen, Tian, Zhu, Yichao, Chang, Jun, Wang, Hong, Zhang, Zhihong, Meng, Fanqing, Wang, Yan, Chen, Yongchang, Xu, Yong, Gu, Luo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466682/
https://www.ncbi.nlm.nih.gov/pubmed/25779663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466682/
https://www.ncbi.nlm.nih.gov/pubmed/25779663

Ejemplares similares