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H4K12ac is regulated by estrogen receptor-alpha and is associated with BRD4 function and inducible transcription

Hormone-dependent gene expression requires dynamic and coordinated epigenetic changes. Estrogen receptor-positive (ER(+)) breast cancer is particularly dependent upon extensive chromatin remodeling and changes in histone modifications for the induction of hormone-responsive gene expression. Our prev...

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Detalles Bibliográficos
Autores principales: Nagarajan, Sankari, Benito, Eva, Fischer, Andre, Johnsen, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466686/
https://www.ncbi.nlm.nih.gov/pubmed/25788266