microRNA-29b prevents liver fibrosis by attenuating hepatic stellate cell activation and inducing apoptosis through targeting PI3K/AKT pathway

microRNA-29b (miR-29b) is known to be associated with TGF-β-mediated fibrosis, but the mechanistic action of miR-29b in liver fibrosis remains unclear and is warranted for investigation. We found that miR-29b was significantly downregulated in human and mice fibrotic liver tissues and in primary act...

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Detalles Bibliográficos
Autores principales: Wang, Jia, Chu, Eagle S.H., Chen, Hai-Yong, Man, Kwan, Go, Minnie Y.Y., Huang, Xiao Ru, Lan, Hui Yao, Sung, Joseph J.Y., Yu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466688/
https://www.ncbi.nlm.nih.gov/pubmed/25356754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466688/
https://www.ncbi.nlm.nih.gov/pubmed/25356754

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