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Regulation of age-related macular degeneration-like pathology by complement factor H
Complement factor H (CFH) is a major susceptibility gene for age-related macular degeneration (AMD); however, its impact on AMD pathobiology is unresolved. Here, the role of CFH in the development of AMD pathology in vivo was interrogated by analyzing aged Cfh(+/−) and Cfh(−/−) mice fed a high-fat,...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466717/ https://www.ncbi.nlm.nih.gov/pubmed/25991857 http://dx.doi.org/10.1073/pnas.1424391112 |