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Angiopoietin-like 4 is a potent angiogenic factor and a novel therapeutic target for patients with proliferative diabetic retinopathy

Diabetic eye disease is the most common cause of severe vision loss in the working-age population in the developed world, and proliferative diabetic retinopathy (PDR) is its most vision-threatening sequela. In PDR, retinal ischemia leads to the up-regulation of angiogenic factors that promote neovas...

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Detalles Bibliográficos
Autores principales: Babapoor-Farrokhran, Savalan, Jee, Kathleen, Puchner, Brooks, Hassan, Syed Junaid, Xin, Xiaoban, Rodrigues, Murilo, Kashiwabuchi, Fabiana, Ma, Tao, Hu, Ke, Deshpande, Monika, Daoud, Yassine, Solomon, Sharon, Wenick, Adam, Lutty, Gerard A., Semenza, Gregg L., Montaner, Silvia, Sodhi, Akrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466723/
https://www.ncbi.nlm.nih.gov/pubmed/26039997
http://dx.doi.org/10.1073/pnas.1423765112