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Angiopoietin-like 4 is a potent angiogenic factor and a novel therapeutic target for patients with proliferative diabetic retinopathy
Diabetic eye disease is the most common cause of severe vision loss in the working-age population in the developed world, and proliferative diabetic retinopathy (PDR) is its most vision-threatening sequela. In PDR, retinal ischemia leads to the up-regulation of angiogenic factors that promote neovas...
Autores principales: | Babapoor-Farrokhran, Savalan, Jee, Kathleen, Puchner, Brooks, Hassan, Syed Junaid, Xin, Xiaoban, Rodrigues, Murilo, Kashiwabuchi, Fabiana, Ma, Tao, Hu, Ke, Deshpande, Monika, Daoud, Yassine, Solomon, Sharon, Wenick, Adam, Lutty, Gerard A., Semenza, Gregg L., Montaner, Silvia, Sodhi, Akrit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466723/ https://www.ncbi.nlm.nih.gov/pubmed/26039997 http://dx.doi.org/10.1073/pnas.1423765112 |
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