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Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3(high) regulatory T cells in humans
CD4(+) regulatory T (Treg) cells expressing CD25 and the transcription factor forkhead box P3 (FOXP3) are indispensable for immunological self-tolerance and homeostasis. FOXP3(+)CD25(+)CD4(+) T cells in humans, however, are heterogeneous in function and differentiation status, including suppressive...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466753/ https://www.ncbi.nlm.nih.gov/pubmed/26015572 http://dx.doi.org/10.1073/pnas.1508224112 |