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Checking the STEP-Associated Trafficking and Internalization of Glutamate Receptors for Reduced Cognitive Deficits: A Machine Learning Approach-Based Cheminformatics Study and Its Application for Drug Repurposing

BACKGROUND: Alzheimer’s disease, a lethal neurodegenerative disorder that leads to progressive memory loss, is the most common form of dementia. Owing to the complexity of the disease, its root cause still remains unclear. The existing anti-Alzheimer’s drugs are unable to cure the disease while the...

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Detalles Bibliográficos
Autores principales: Jamal, Salma, Goyal, Sukriti, Shanker, Asheesh, Grover, Abhinav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466797/
https://www.ncbi.nlm.nih.gov/pubmed/26066505
http://dx.doi.org/10.1371/journal.pone.0129370