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Associations of chemo- and radio-resistant phenotypes with the gap junction, adhesion and extracellular matrix in a three-dimensional culture model of soft sarcoma

BACKGROUND: Three-dimensional (3D) culture models are considered to recapitulate the cell microenvironment in solid tumors, including the extracellular matrix (ECM), cell-cell interactions, and signal transduction. These functions are highly correlated with cellular behaviors and contribute to resis...

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Detalles Bibliográficos
Autores principales: Bai, Chujie, Yang, Min, Fan, Zhengfu, Li, Shu, Gao, Tian, Fang, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467058/
https://www.ncbi.nlm.nih.gov/pubmed/26055407
http://dx.doi.org/10.1186/s13046-015-0175-0