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STUMP un“stumped”: anti-tumor response to anaplastic lymphoma kinase (ALK) inhibitor based targeted therapy in uterine inflammatory myofibroblastic tumor with myxoid features harboring DCTN1-ALK fusion

BACKGROUND: Recurrent, metastatic mesenchymal myxoid tumors of the gynecologic tract present a management challenge as there is minimal evidence to guide systemic therapy. Such tumors also present a diagnostic dilemma, as myxoid features are observed in leiomyosarcomas, inflammatory myofibroblastic...

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Detalles Bibliográficos
Autores principales: Subbiah, Vivek, McMahon, Caitlin, Patel, Shreyaskumar, Zinner, Ralph, Silva, Elvio G, Elvin, Julia A., Subbiah, Ishwaria M., Ohaji, Chimela, Ganeshan, Dhakshina Moorthy, Anand, Deepa, Levenback, Charles F., Berry, Jenny, Brennan, Tim, Chmielecki, Juliann, Chalmers, Zachary R., Mayfield, John, Miller, Vincent A., Stephens, Philip J., Ross, Jeffrey S., Ali, Siraj M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467062/
https://www.ncbi.nlm.nih.gov/pubmed/26062823
http://dx.doi.org/10.1186/s13045-015-0160-2