Interlocus gene conversion explains at least 2.7 % of single nucleotide variants in human segmental duplications

BACKGROUND: Interlocus gene conversion (IGC) is a recombination-based mechanism that results in the unidirectional transfer of short stretches of sequence between paralogous loci. Although IGC is a well-established mechanism of human disease, the extent to which this mutagenic process has shaped ove...

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Detalles Bibliográficos
Autor principal: Dumont, Beth L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467073/
https://www.ncbi.nlm.nih.gov/pubmed/26077037
http://dx.doi.org/10.1186/s12864-015-1681-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467073/
https://www.ncbi.nlm.nih.gov/pubmed/26077037
http://dx.doi.org/10.1186/s12864-015-1681-3

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