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Genetic Variants in Caveolin-1 and RhoA/ROCK1 Are Associated with Clear Cell Renal Cell Carcinoma Risk in a Chinese Population

BACKGROUND: The RhoA/ROCK pathway and Caveolin-1 (Cav-1) participate in the process of tumorigenesis in numerous types of cancer. Up-regulation of RhoA/ROCK and Cav-1 expression is considered to be associated with the development and progression of clear cell renal cell carcinoma (ccRCC). We investi...

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Detalles Bibliográficos
Autores principales: Zhao, Ruizhe, Liu, Kang, Huang, Zhengkai, Wang, Jun, Pan, Yongsheng, Huang, Yuan, Deng, Xiaheng, Liu, Jinliang, Qin, Chao, Cheng, Gong, Hua, Lixin, Li, Jie, Yin, Changjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467078/
https://www.ncbi.nlm.nih.gov/pubmed/26066055
http://dx.doi.org/10.1371/journal.pone.0128771