Targeting tumor-initiating cells: Eliminating anabolic cancer stem cells with inhibitors of protein synthesis or by mimicking caloric restriction

We have used an unbiased proteomic profiling strategy to identify new potential therapeutic targets in tumor-initiating cells (TICs), a.k.a., cancer stem cells (CSCs). Towards this end, the proteomes of mammospheres from two breast cancer cell lines were directly compared to attached monolayer cells...

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Detalles Bibliográficos
Autores principales: Lamb, Rebecca, Harrison, Hannah, Smith, Duncan L., Townsend, Paul A., Jackson, Thomas, Ozsvari, Bela, Martinez-Outschoorn, Ubaldo E., Pestell, Richard G., Howell, Anthony, Lisanti, Michael P., Sotgia, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467101/
https://www.ncbi.nlm.nih.gov/pubmed/25671304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467101/
https://www.ncbi.nlm.nih.gov/pubmed/25671304

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