Inhibition of EP2/EP4 signaling abrogates IGF-1R-mediated cancer cell growth: Involvement of protein kinase C-θ activation

Associations between growth factor receptor-mediated cell signaling and cancer cell growth have been previously characterized. Receptors for prostaglandin E(2), such as EP2, and EP4, play roles in cancer growth, progression and invasion. Thus, we examined the interactions between EP2/EP4- and IGF-1R...

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Detalles Bibliográficos
Autores principales: Takahashi, Tetsuyuki, Uehara, Hisanori, Ogawa, Hirohisa, Umemoto, Hitomi, Bando, Yoshimi, Izumi, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467118/
https://www.ncbi.nlm.nih.gov/pubmed/25638159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467118/
https://www.ncbi.nlm.nih.gov/pubmed/25638159

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