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Inhibition of EP2/EP4 signaling abrogates IGF-1R-mediated cancer cell growth: Involvement of protein kinase C-θ activation
Associations between growth factor receptor-mediated cell signaling and cancer cell growth have been previously characterized. Receptors for prostaglandin E(2), such as EP2, and EP4, play roles in cancer growth, progression and invasion. Thus, we examined the interactions between EP2/EP4- and IGF-1R...
Autores principales: | Takahashi, Tetsuyuki, Uehara, Hisanori, Ogawa, Hirohisa, Umemoto, Hitomi, Bando, Yoshimi, Izumi, Keisuke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467118/ https://www.ncbi.nlm.nih.gov/pubmed/25638159 |
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