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A melanoma subtype with intrinsic resistance to BRAF inhibition identified by receptor tyrosine kinases gene-driven classification

Dysregulation of receptor tyrosine kinases (RTKs) contributes to several aspects of oncogenesis including drug resistance. In melanoma, distinct RTKs have been involved in BRAF inhibitors (BRAFi) resistance, yet the utility of RTKs expression pattern to identify intrinsically resistant tumors has no...

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Detalles Bibliográficos
Autores principales: Dugo, Matteo, Nicolini, Gabriella, Tragni, Gabrina, Bersani, Ilaria, Tomassetti, Antonella, Colonna, Valentina, Del Vecchio, Michele, De Braud, Filippo, Canevari, Silvana, Anichini, Andrea, Sensi, Marialuisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467137/
https://www.ncbi.nlm.nih.gov/pubmed/25742786