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Traditional Chinese medicine herbal mixture LQ arrests FUCCI-expressing HeLa cells in G(0)/G(1) phase in 2D plastic, 2.5D Matrigel(®), and 3D Gelfoam(®) culture visualized with FUCCI imaging

We used the fluorescence ubiquitination-based cell cycle indicator (FUCCI) to monitor cell cycle arrest after treatment of FUCCI-expressing HeLa cells (FUCCI-HeLa) with a traditional Chinese medicine (TCM) herbal mixture LQ, previously shown to have anti-tumor and anti-metastatic activity in mouse m...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Wu, Chengyu, Bouvet, Michael, Yano, Shuya, Hoffman, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467149/
https://www.ncbi.nlm.nih.gov/pubmed/25779660