Frequencies of SF3B1, NOTCH1, MYD88, BIRC3 and IGHV mutations and TP53 disruptions in Chinese with chronic lymphocytic leukemia: disparities with Europeans

We studied 307 consecutive Chinese with chronic lymphocytic leukemia (CLL) in diverse disease-stages before and after diverse therapies for mutations in several CLL-related genes. Mutation frequencies were SF3B1, 5%, NOTCH1, 8%, MYD88, 8%, BIRC3, 2%, TP53, 15% and IGHV, 60%. Several of these frequen...

Descripción completa

Detalles Bibliográficos
Autores principales: Xia, Yi, Fan, Lei, Wang, Li, Gale, Robert Peter, Wang, Man, Tian, Tian, Wu, Wei, Yu, Liang, Chen, Yao-Yu, Xu, Wei, Li, Jian-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Clinical Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467158/
https://www.ncbi.nlm.nih.gov/pubmed/25605254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467158/
https://www.ncbi.nlm.nih.gov/pubmed/25605254

Ejemplares similares