Cargando…
Differential signaling mechanism for HIV-1 Nef-mediated production of IL-6 and IL-8 in human astrocytes
Variety of HIV-1 viral proteins including HIV-1 Nef are known to activate astrocytes and microglia in the brain and cause the release of pro-inflammatory cytokines, which is thought to be one of the mechanisms leading to HIV-1- mediated neurotoxicity. IL-6 and IL-8 have been found in the CSF of pati...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467202/ https://www.ncbi.nlm.nih.gov/pubmed/26075907 http://dx.doi.org/10.1038/srep09867 |