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The pharmacokinetic effect of coadministration of apremilast and methotrexate in individuals with rheumatoid arthritis and psoriatic arthritis

Apremilast is a novel agent for the treatment of inflammatory based autoimmune disorders. The objective of this study was to assess the pharmacokinetic effects of co administration of apremilast and methotrexate on both agents. This was an open-label, multi-center, 3-treatment period, sequential stu...

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Detalles Bibliográficos
Autores principales: Liu, Yong, Zhou, Simon, Nissel, James, Wu, Anfan, Lau, Henry, Palmisano, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467241/
https://www.ncbi.nlm.nih.gov/pubmed/26097790
http://dx.doi.org/10.1002/cpdd.109