Pharmacokinetics of Single-Dose Dolutegravir in HIV-Seronegative Subjects With Moderate Hepatic Impairment Compared to Healthy Matched Controls

This study evaluated dolutegravir pharmacokinetics (PK) in subjects with moderate hepatic impairment compared to matched, healthy controls. In this open-label, parallel-group study, eight adult subjects with moderate hepatic impairment (Child-Pugh Score 7–9) and eight healthy subjects matched for ge...

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Detalles Bibliográficos
Autores principales: Song, Ivy H, Borland, Julie, Savina, Paul M, Chen, Shuguang, Patel, Parul, Wajima, Toshihiro, Peppercorn, Amanda F, Piscitelli, Stephen C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2013
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467250/
https://www.ncbi.nlm.nih.gov/pubmed/26097786
http://dx.doi.org/10.1002/cpdd.55

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467250/
https://www.ncbi.nlm.nih.gov/pubmed/26097786
http://dx.doi.org/10.1002/cpdd.55

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