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Absence of QTc Prolongation with Domperidone: A Randomized, Double-Blind, Placebo- and Positive-Controlled Thorough QT/QTc Study in Healthy Volunteers

Domperidone effects on QTc duration were assessed in a single-center, double-blind, four-way crossover study of 44 healthy participants randomized to one of four treatment sequences consisting of four treatment periods separated by 4–9 days washout. On Day 1 of each 4-day period, participants began...

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Detalles Bibliográficos
Autores principales: Biewenga, Jeike, Keung, Chi, Solanki, Bhavna, Natarajan, Jaya, Leitz, Gerhard, Deleu, Sofie, Soons, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467253/
https://www.ncbi.nlm.nih.gov/pubmed/26097791
http://dx.doi.org/10.1002/cpdd.126