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Absence of QTc Prolongation with Domperidone: A Randomized, Double-Blind, Placebo- and Positive-Controlled Thorough QT/QTc Study in Healthy Volunteers
Domperidone effects on QTc duration were assessed in a single-center, double-blind, four-way crossover study of 44 healthy participants randomized to one of four treatment sequences consisting of four treatment periods separated by 4–9 days washout. On Day 1 of each 4-day period, participants began...
Autores principales: | Biewenga, Jeike, Keung, Chi, Solanki, Bhavna, Natarajan, Jaya, Leitz, Gerhard, Deleu, Sofie, Soons, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467253/ https://www.ncbi.nlm.nih.gov/pubmed/26097791 http://dx.doi.org/10.1002/cpdd.126 |
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