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Pseudogene INTS6P1 regulates its cognate gene INTS6 through competitive binding of miR-17-5p in hepatocellular carcinoma

The complex regulation of tumor suppressive gene and its pseudogenes play key roles in the pathogenesis of hepatocellular cancer (HCC). However, the roles played by pseudogenes in the pathogenesis of HCC are still incompletely elucidated. This study identifies the putative tumor suppressor INTS6 and...

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Detalles Bibliográficos
Autores principales: Peng, Haoran, Ishida, Masaharu, Li, Ling, Saito, Atsushi, Kamiya, Atsushi, Hamilton, James P., Fu, Rongdang, Olaru, Alexandru V., An, Fangmei, Popescu, Irinel, Iacob, Razvan, Dima, Simona, Alexandrescu, Sorin T., Grigorie, Razvan, Nastase, Anca, Berindan-Neagoe, Ioana, Tomuleasa, Ciprian, Graur, Florin, Zaharia, Florin, Torbenson, Michael S., Mezey, Esteban, Lu, Minqiang, Selaru, Florin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467393/
https://www.ncbi.nlm.nih.gov/pubmed/25686840