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Somatic microsatellite variability as a predictive marker for colorectal cancer and liver cancer progression

Microsatellites (MSTs) are short tandem repeated genetic motifs that comprise ~3% of the genome. MST instability (MSI), defined as acquired/lost primary alleles at a small subset of microsatellite loci (e.g. Bethesda markers), is a clinically relevant marker for colorectal cancer. However, these mar...

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Detalles Bibliográficos
Autores principales: Vaksman, Zalman, Garner, Harold R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467400/
https://www.ncbi.nlm.nih.gov/pubmed/25691061